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However, studies in animals have shown that semaglutide interacts with the circumventricular regions and specifically accesses GLP-1Rpositive brain regions following peripheral administration, including the area postrema in the hindbrain, the arcuate nucleus of the hypothalamus, and the lateral septal nucleus [50]

Stopping the medication may lead to weight regain if lifestyle habits and metabolic factors are not maintained.

The most common side effects include: Nausea Vomiting Diarrhea Dizziness Headaches Indigestion Low blood sugar Severe side effects are also possible, though rare

Semaglutide can interact with medications that affect blood sugar, such as insulin